Sunday, May 19, 2013

 Q: Out of following which treatment would NOT work in active bleeding from Uremia?

A) Desmopressin (DDAVP)
B) Hemodialysis
C) IV Estrogen
D) PO Estrogen
E) Cryoprecipitate




Answer:  B

Interestingly, Dialysis is very efective in preventing uremic bleeding but has no role in active bleeding from uremia. DDAVP is the most potent remedy in such situations followed by cryoprecipitate. Estrogen (IV or PO) has also shown some effectiveness.

Please see following article for more reading

Evidence-based treatment recommendations for uremic bleeding- Stephanie J Hedges, Sarah B Dehoney, Justin S Hooper, Jamshid Amanzadeh and Anthony J Busti

Reference: NATURE CLINICAL PRACTICE NEPHROLOGY,  MARCH 2007 VOL 3 NO 3

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