Q: Central Pontine Myelinolysis (CPM) may be a complication of which surgery?
Answer: Complication of Liver transplant surgery
This complication is distinct from other causes of central pontine myelinolysis like
- chronic alcoholism
- rapid correction of hyponatremia
- occasionally after rapid correction of hypernatremia.
- Wlison's disease
- Burn patients (with a prolonged period of serum hyperosmolality)
Singh N, Yu VL, Gayowski T. Central nervous system lesions in adult liver transplant recipients: clinical review with implications for management. Medicine (Baltimore). Mar 1994;73(2):110-8.
Adams RD, Victor M, Mancall EL. Central pontine myelinolysis: a hitherto undescribed disease occurring in alcoholic and malnourished patients. AMA Arch Neurol Psychiatry. Feb 1959;81(2):154-72.
Kumar S, Fowler M, Gonzalez-Toledo E, Jaffe SL. Central pontine myelinolysis, an update. Neurol Res. Apr 2006;28(3):360-6.