icupearls.org Archive

Pearls on Intensive Care Medicine Practice - Project "Critical Care A Day"

Sunday, June 29, 2025

Flumazenil use in non-benzodiazepine overdose

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Q: Flumazenil can be an effective antidote for which other drugs besides benzodiazepines? Answer: Flumazenil is traditionally used as an an...
Saturday, June 28, 2025

Stool osmolality

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Q : By default, stool osmolality is equal to plasma osmolality. A) True B) False Answer: A Normal fecal fluid's osmolality is about equa...
Friday, June 27, 2025

Bicarb in severe LA

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Q : All of the following are potential effects of bicarbonate therapy in lactic acidosis EXCEPT? - select one A) increase partial pressure o...
Thursday, June 26, 2025

unconventional uses of Haloperidol

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Q: Give some unconventional uses of Haloperidol? Answer : Although Haldol has slowly lost its charm in the ICU over the years due to the av...
Wednesday, June 25, 2025

electric shock radiating down with flexion of the neck

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Q:  32 years old female with a known history of Multiple Sclerosis (MS) presented with complaints of an electric shock radiating down as she...
Tuesday, June 24, 2025

IM

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Q : Why is Infectious mononucleosis (IM) called Infectious mononucleosis (IM) ? Answer:  This question aims to teach the habit of understand...
Monday, June 23, 2025

Ganciclovir and Valganciclovir

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Q: What is the difference between Ganciclovir and Valganciclovir? Answer:   Ganciclovir and Valganciclovir are the mainstay of cytomegalovir...
Saturday, June 21, 2025

K-Phos

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Q:  21 years old female with Anorexia Nervosa is admitted to the ICU with severe electrolyte imbalance.  The patient has been prescribed ...
Friday, June 20, 2025

goiter and choking

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Q : 53 years old female presented with progressively worsening choking sensation over months. On exam, noticed to have stridor. CT chest and...
Wednesday, June 18, 2025

Vision loss in pHTN patient

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Q: 44 years old female with underlying pulmonary hypertension (pHTN), recently discharged from the hospital, presented back to the ED with v...
Tuesday, June 17, 2025

Yellow fever- Rx

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Q:  What is the mainstay of treatment for yellow fever? - select one A) IgG monoclonal antibody B) Ribavirin  C) Sofosbuvir  D) Plasma excha...
Sunday, June 15, 2025

Electrolytes in GBS

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Q:  Which electrolyte disturbance is more common in patients with Guillain-BarrĂ© syndrome (GBS) who develop dysautonomia? A) Hypernatremia B...

IV Vitamin K and Warfarin

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Q : One dose of intravenous (IV) Vitamin K antagonizes the effects of warfarin for how many days? Answer:  About one week A high dose of Vit...
Saturday, June 14, 2025

Sildenafil with inhaled NO

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Q : What is the advantage of adding Sildenafil with inhaled NO (iNO) in the treatment of pulmonary hypertension? Answer: Sildenafil not only...
Friday, June 13, 2025

Balint syndrome

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Q: What is Balint syndrome? Answer: Balint syndrome, initially described as psychic paralysis of visual fixation (a misnomer) 70 years ago,...
Thursday, June 12, 2025

PE in schizophrenia

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Q:  59 years female with schizophrenia presented to ED with Shortness of Breath (SOB).  Wife reports that recently patient was having a bout...
Wednesday, June 11, 2025

Abdominal exam in ACS

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Q:  44 years old male is admitted to the ICU with severe acute pancreatitis after a bout of binge drinking at a Saturday night party.  Patie...
Tuesday, June 10, 2025

Cefiderocol

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Q: Cefiderocol belongs to which generation of cephalosporins? - select one A) First generation  B) Second generation  C) Third generation D...
Monday, June 9, 2025

Basis of rouleaux formation

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Q: What's the basis of Rouleaux formation in diseases with increased levels of plasma proteins? Answer: When red blood cells (RBCs) stac...
Sunday, June 8, 2025

MALA and bicarb

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Q : 56 years old male is admitted to the ICU with an intentional overdose of Metformin.  Patient is in severe refractory shock, lactic acid...
Saturday, June 7, 2025

compensatory changes to maintain oxygen delivery in acute anemia

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Q: In an isovolemic healthy person, acute reduction in the hemoglobin (Hb) concentration induces all of the following compensatory changes ...
Friday, June 6, 2025

Common drug interaction in cardiac patients

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Case:  58 years old male is admitted to the ICU with Atrial fibrillation with RVR (rapid ventricular rate).  The patient did well with rate ...
Thursday, June 5, 2025

ALDEN

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Q:  ALDEN is an algorithm to determine the causality of which disease? Answer: Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)...
Wednesday, June 4, 2025

HbA1C in ESRD

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Q:  In end-stage renal Disease (ESRD) patients, Glycated hemoglobin (A1C) is a better reflection of blood glucose control than daily or cont...
Tuesday, June 3, 2025

Numbers in calculated Posm formula

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Q : Why we multiply Na by 2 in the formula in calculated Plasma osmolalilty whose formula is 2  x  Plasma Na (mEq/L) + [Glucose]/18 + Blood ...
Monday, June 2, 2025

WBC in DKA

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Q : Leukocytosis in Diabetic ketoacidosis (DKA) is proportional to the degree of ketonemia. A) True B) False Answer : A (True) DKA is classi...
Sunday, June 1, 2025

Pregnancy and Bell's palsy

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Q: 26 years old pregnant female is admitted to ICU with hypertensive crises and Bell's palsy. In which trimester is the risk of Bell...
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Saturday, May 31, 2025

Non infectious causes of acidotic pleural fluid acidosis

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Q: Beside infection give at least five causes of acidotic pleural fluid acidosis with or without low glucose? Answer : Complicated parapneu...
Friday, May 30, 2025

Radial Artery in CABG

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Q: In which subset of patients should the radial artery graft be used cautiously in cardiac arterial bypass surgery (CABG)? Answer: Renal ...
Thursday, May 29, 2025

renal failure treated by ACE-I

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Q : Which type of renal failure is treated/managed by ACE inhibitors? Answer : Scleroderma Renal Crisis! Scleroderma Renal Crisis is one of ...
Wednesday, May 28, 2025

Thyroid and Recurrent Pregnancy loss connection

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Case: 36 years old woman is admitted to the ICU for severe depression and suicidal ideation since she had three consecutive losses of pregn...
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