Q: 62 year old male with history of Acute Intermittent Porphyria (AIP) presented to ER with chest pain. While awaiting to go to cardiac cath. patient went  into ventricular fibrillation. Which one antiarrhythmic medicine is contra-indicated or at least should be given with extreme caution?



Answer: Lidocaine

Contraindications for the use of lidocaine include history of Porphyria, especially acute porphyria. Lidocaine is known to be porphyrogenic.