The sepsis six is following intervention in one hour
- Deliver high-flow oxygen.
- Take blood cultures.
- Administer empiric intravenous antibiotics.
- Measure serum lactate and send full blood count.
- Start intravenous fluid resuscitation.
- Commence accurate urine output measurement.
Five years after the international Surviving Sepsis Campaign (SSC) care bundles were published, care standards in the management of patients with severe sepsis are achieved in fewer than one in seven patients! Application of sepsis six along with SSC resuscitation bundle showed remarkable improvement.
Study data from 567 patients showed that 84.6% of those receiving the sepsis six (n=220) achieved the resuscitation bundle compared with only 5.8% of others!
The sepsis six and the severe sepsis resuscitation bundle: a prospective observational cohort study - Emerg Med J 2011;28:507-512
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