Q: What is the conversion of IV to PO Tylenol (Acetaminophen)?


Answer: 1:1

FDA has approved the IV form of Tylenol (Omfirmev). It has the advantage of opioid sparing effect and very useful in immediate post-op period. Peak serum levels are 70% higher with IV form, with onset of analgesia at 10 minutes, peak at 1 hour and last 4-6 hours.