Saturday, March 24, 2012

Q: Sotalol 

 A) prolongs the PR interval 
 B) prolongs the QT interval 
 C) is a non-selective β blocker 
 D) may increase risk of death with decreased ejection fraction. 
 E) All of the above 


Answer: E 

 Sotalol is a non-selective competitive β-adrenergic receptor blocker that also exhibits Class III antiarrhythmic properties by its inhibition of potassium channels. 

 Though it can be use to treat hypertension, it is mostly used to treat ventricular tachycardias and atrial fibrillation. 

 Some evidence suggests that sotalol should be avoided in the setting of decreased ejection fraction due to an increased risk of death.

No comments:

Post a Comment