Washout gradient of Troponin in myocardial reperfusion

Myocardial reperfusion, (spontaneous or via lytics or PCI), affect the kinetics of troponin. Patients with ST-segment elevation myocardial infarction who achieve an effective reperfusion have a faster return to normal – called ‘‘wash-out phenomenon’’. The ratio between the concentrations at these two points can be used to discriminate between successful and unsuccessful reperfusion. In general, the greater the ratio (at least 5), the more likely it is that reperfusion has occurred.