Q:
It is a common practice to give calcium to
counteract aarrhythmias. But in which condition, it may not be a good move or
actually, it may be harmful to the patient?
Anwer: In a
digitalized patient
Digoxin inhibits the
Na+/K+-ATPase(exchanges 2 K for 3Na) in the cardiac
myocyte by competing with potassium,and causes intracellular sodium
concentration to increase. This then leads to an accumulation of intracellular
calcium by blocking the Na+-Ca++ exchange system.
In patients
on Digoxin, if more calcium is given it can lead to more intracellular calcium
in mycocyte leading to what has been described as cardiac tetany due to
prolonged depolarisation.
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