Q: Although Vancomycin remained the treatment of choice for MRSA Pneumonia due to its high cost effectiveness, but what advantage does Zyvox (Linezolid) has over Vancomycin in lung related infections?


Answer: Linezolid is better than vancomycin against nosocomial pneumonia, like MRSA ventilator-associated pneumonia because the penetration of linezolid into bronchial fluids is much higher than that of vancomycin.

Other minor advatanges include high bioavailability, easy switching to oral therapy and no required adjustments in renal failure.