Hyponatremia and non-cardiogenic pulmonary edema

 

 

One less paid attention during management of hyponatremia is to non-cardiogenic pulmonary edema, which can develop at Sodium level below 121 ± 3 mmol/L. In these settings usually EKG and echocardiograms are normal. CXR shows pulmonary edema with a normal heart. Also, cardiac enzymes are normal, and pulmonary wedge pressure not elevated. Cerebral edema may simultaneously may be present. Situation is usually reversible with reversal of hyponatremia.

 

 

 

Reference:

 

 

1. J. Carlos Ayus, MD; Joseph Varon, MD; and Allen I. Arieff, MD Hyponatremia, Cerebral Edema, and Noncardiogenic Pulmonary Edema in Marathon Runners, Ann Intern Med. 2000;132(9):711-714

 

2. Ayus JC, Arieff AI., Pulmonary complications of hyponatremic encephalopathy. Noncardiogenic pulmonary edema and hypercapnic respiratory failure., Chest. 1995 Feb;107(2):517-21.