Q: 36 year old female is in ICU with septic shock and diagnosed with strongyloidiasis. She also has severe GI ileus and was made NPO . She is on ivermectin. What is your option to administer her essential treatment?
Answer: Rectal or SC administration of Ivermectin
Ivermectin is the drug of choice for strongyloidiasis. It is usually given as PO with empty stomach but if PO route is note feasible, it can be given rectally or even as SC administration.
Fusco DN, Downs JA, Satlin MJ, Pahuja M, Ramos L, Barie PS, et al. Non-oral treatment with ivermectin for disseminated strongyloidiasis. Am J Trop Med Hyg. Oct 2010;83(4):879-83