Q;
What is the significance of
increased Troponin in Pulmonary Embolism?
Answer:
In acute pulmonary
embolism, troponins probably rise because of acute right heart overload. The
release is of shorter duration than in unstable angina, and the peak level is
linked to the outcome.
References:
1. Müller-Bardorff M, Weidtmann B, Giannitsis E, et al.
Release kinetics of cardiac troponin T in survivors of confirmed severe
pulmonary embolism. Clin Chem. 2002; 48: 673–675.
2. Giannitsis E, Müller-Bardorff M, Kurowski V, et al. Independent prognostic value of cardiac troponin T in patients with confirmed pulmonary embolism. Circulation. 2000; 102: 211–217
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