Q: Which common conditions encountered in ICU may give falsely normal or higher level of Pre-albumin?
Answer:
1. Alcoholics may have elevated levels of prealbumin after binge drinking. In acute alcohol intoxication, a leakage of proteins from damaged hepatic cells may cause a rise in the prealbumin level. It takes about a week, when levels return to baseline.
2. Prednisone therapy may cause falsely higher prealbumin levels.
3. Patients on chronic progestational agents may have falsely higher prealbumin level.
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