Thursday, December 12, 2013

Q: How female gender effects TRALI (Transfusion related acute lung injury)?
Answer: 

Plasma from female donors is associated with an increased risk of TRALI, while RBCs from female donors are not.
Reference:

Middelburg RA, Van Stein D, Zupanska B, Uhrynowska M, Gajic O, Muñiz-Diaz E, Galvez NN, Silliman CC, Krusius T, Wallis JP, Vandenbroucke JP, Briët E, Van Der Bom JG. - Female donors and transfusion-related acute lung injury: A case-referent study from the International TRALI Unisex Research Group. Transfusion. 2010 Nov;50(11):2447-54.

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