Thursday, December 5, 2013

Q: What are the less well know risk factors for C.Diff. Colitis in ICU beside previous antibiotics usage, age and severity of illness?
Answer:
  1. Antacid therapy
  2. Stool softeners
  3. Nasogastric or oro-gastric tubes
  4. Enteral feeds
  5. Cathartics

References:

1. Poutanen SM, Simor AE: Clostridium difficile–associated diarrhea in adults. CMAJ 2004;171:51-58

2. Thielman NM, Wilson KH: Antibiotic-associated colitis -  Mandell GL, Bennett JE, Dolin R (eds): Principles and Practice of Infectious Diseases, 6th ed, vol 1. Philadelphia: Elsevier, 2005, pp 1249-1262.

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