A note on Magnesium level and Hemolysis

Magnesium concentrates in erythrocytes almost three times more than in serum. Hemolysis can increase plasma magnesium. Hypermagnesemia is expected only in massive hemolysis. The serum Mg is expected to rise by 0.1 mEq/L for every 250 mL of erythrocytes that lyse completely, so hypermagnesemia is expected only with massive hemolysis.