Q: You have been called to ER to evaluate a patient with severe headache. You ruled out SAH (Subarachnoid hemorrhage) with radiological imagings and you strongly suspect acute migraine. What one non-narcotic medicine may help you to treat severe acute migraine? 

Answer: Metoclopramide

A meta-analysis of 13 randomized controlled trials concluded that intravenous metoclopramide should be considered a primary agent in the treatment of migraine in emergency departments.

Reference:

Colman I, Brown MD, Innes GD, Grafstein E, Roberts TE, Rowe BH. Parenteral metoclopramide for acute migraine: meta-analysis of randomised controlled trials. BMJ. 2004;329(7479):1369–1373