Q: Which drug is found to be associated with Vasoplegia Syndrome in post cardiac surgery patients?
Answer: ACE inhibitors and ARBs
Though there is a weak evidence, but many reports have suggested that preoperative administration of ACEI/ARBs in patients undergoing cardiac surgery contributes to lowering of SVR (vasoplegia syndrome) postoperatively. It is also suggested, if possible to hold ACEI/ARBs 24 hours before cardiac surgery to avoid postoperative vasodilation.
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