Q: 74 year old male with Parkinson's Disease is admitted to ICU with
Urosepsis. Patient is recovering well. A night before transfer to floor, patient
start displaying signs of delirium and psychosis. Which anti-psychotic would be
of use?
Answer:
Quetiapine
Quetiapine and clozapine
are recommended for the treatment of Parkinson's disease related psychosis because
of their low extrapyramidal side effects. Clozapine is known for some heavy side
effects alike agranulocytosis, therefore quetiapine would be considered as a
better choice.
Reference:
Shotbolt P, Samuel M, David A (November 2010). "Quetiapine in
the treatment of psychosis in Parkinson’s disease". Therapeutic Advances in
Neurological Disorders 3 (6): 339–350
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