Wednesday, November 26, 2014

Q: Which atypical anti-psychotic drug can also be used as an anti-emetic in chemotheray induced nausea and vomitting?


Answer: Olanzapine

Olanzapine can be use as an anti-emetic, particularly in chemotherapy-induced nausea and vomiting. It is highly effective if use as a cocktail with palonosetron and dexamethasone. 



Reference:

Navari RM, Einhorn LH, Loehrer PJ, Passik SD, Vinson J, McClean J, Chowhan N, Hanna NH, Johnson CS (2007). "A phase II trial of olanzapine, dexamethasone, and palonosetron for the prevention of chemotherapy-induced nausea and vomiting: A Hoosier oncology group study". Supportive Care in Cancer 15 (11): 1285–91.

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