Q:
Which atypical anti-psychotic drug can also be used as an anti-emetic in
chemotheray induced nausea and vomitting?
Answer: Olanzapine
Olanzapine can be use as
an anti-emetic, particularly in chemotherapy-induced nausea and vomiting. It is
highly effective if use as a cocktail with palonosetron and
dexamethasone.
Reference:
Navari RM, Einhorn LH, Loehrer PJ, Passik SD, Vinson J,
McClean J, Chowhan N, Hanna NH, Johnson CS (2007). "A phase II trial of
olanzapine, dexamethasone, and palonosetron for the prevention of
chemotherapy-induced nausea and vomiting: A Hoosier oncology group study".
Supportive Care in Cancer 15 (11): 1285–91.
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