Q: Tumor Lysis Syndrome can do all of the following except:

A) Hyperkalemia

B) Hyperphosphatemia

C) Hypercalcemia

D) Hyperuricemia


Answer: C

Tumor Lysis syndrome causes hypocalcemia instead of hypercalcemia

Cairo and Bishop defined a classification system for tumor lysis syndrome dividing it into categories

Laboratory tumor lysis syndrome: 
(abnormality in 2 or more of the following, occurring within three days before or seven days after chemotherapy).

• uric acid > 8 mg/dL or 25% increase
• potassium > 6 meq/L or 25% increase
• phosphate > 4.5 mg/dL or 25% increase
• calcium < 7 mg/dL or 25% decrease

Clinical tumor lysis syndrome: 
(laboratory tumor lysis syndrome plus one or more of the following)

• increased serum creatinine (1.5 times upper limit of normal)
• cardiac arrhythmia or sudden death
• seizure

Reference:

Cairo MS, Bishop M (October 2004). "Tumour lysis syndrome: new therapeutic strategies and classification". Br. J. Haematol. 127 (1): 3–11.