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When a person doing CPR tires, the patient's end-tidal CO2 falls. Its time to change the guard, so a fresh rescuer takes over.
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When a patient experiences return of spontaneous circulation (ROSC), the first sign is often a sudden rise in the ETCO2 as the rush of circulation washes untransported CO2 from the tissues.
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A sudden drop in ETCO2 indicates that the patient has lost pulses and CPR may need to be initiated.
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