Q: 24 year old female diagnosed with HELLP syndrome, continue to get worse clinically despite delivery of baby and all conventional treatment. What is your next option?

Answer: Plasmapheresis

Plasma exchange therapy can be very helpful in patients with post-partum hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome who are refractory to treatment.  Rapid improvement of the platelet, AST, ALT and LDH levels is expected.