A note on Fospropofol

 Fospropofol is a water-soluble propofol prodrug. It has various advantage due to its water solubility like less pain at the site of IV infusion, so can be given via peripheral IV with more comfort. It carries less chance for hyperlipidemia, and subsequently less chance for bacteremia. Because of said advantage, it is a good choice for use in short-term sedation for patients undergoing procedures such as endoscopy. Fospropofol is metabolized by alkaline phosphatases to propofol, formaldehyde, and phosphate.