Thursday, August 6, 2015

Q: In acute Pancreatitis which IVF is preferred?


Answer: Lactated Ringer's (LR)

Though evidence is weak but at least one small study of 40 patients showed that fluid resuscitation with lactated Ringer's in acute pancreatitis may be more beneficial. Patients who received lactated Ringer's had significantly lower mean C-reactive protein (CRP) levels compared with patients who received normal saline (52 versus 104 mg/dL) and also a significantly less systemic inflammatory response syndrome (SIRS) after 24 hours (84 versus 0 percent). 


Reference:

Wu BU, Hwang JQ, Gardner TH, et al. Lactated Ringer's solution reduces systemic inflammation compared with saline in patients with acute pancreatitis. Clin Gastroenterol Hepatol 2011; 9:710.


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