Q: In hemolytic Anemia? (Choose one)

A) LDH goes up, Reticulocyte count goes up, Indirect bilirubin goes up
B)  LDH goes up, Reticulocyte count goes up, Direct bilirubin goes up
C)  LDH goes up, Reticulocyte count goes up, Serum haptoglobin goes up
D)  LDH goes down, Reticulocyte count goes up, Serum haptoglobin goes down
E)  LDH goes down, Reticulocyte count goes down, Serum haptoglobin goes up



Answer: A

Hemolytic Anemia is a common entity in ICU particularly if any device is cannulated to patient. Few simple tips to diagnose hemolytic anemia is 

•  Increased indirect bilirubin concentration 
• Splenomegaly 
• Increased serum lactate dehydrogenase (LDH) concentration 
• Reduced or absent level of serum haptoglobin 
• Increased reticulocyte percentage or absolute reticulocyte number