Q: What is the usual liver function test (LFT) pattern indicative of liver failure secondary to Wilson's Disease?


Answer:  A ratio of alkaline phosphatase* to total bilirubin^ of less than four.

In Wilson's disease, LFT demonstrate total bilirubin elevation way out of proportion to alkaline phosphatase, which on the other spectrum is usually very low. 


*international units/L
^mg/dL