Q: All of the following can be prescribed to patient with sickle cell crisis as an adjuvant except?

A) Folic acid 
B) Vitamin D
C) Magnesium
D) Vitamin C
E) Iron



Answer: E

Iron overload is a major risk and a complication in patients with sickle cell disease (SCD). Most of these patients, by the time they reach adulthood, have enough blood transfusions to have iron overload. On the contrary, patients with SCD are usually candidates for iron chelation therapy.



Reference:

 P. B. Walter, P. Harmatz, and E. Vichinsky, “Iron metabolism and iron chelation in sickle cell disease,” Acta Haematologica, vol. 122, no. 2-3, pp. 174–183, 2009.