Q: Inhaled Nitric Oxide(NO) increases the risk of injury to which of the following organs

A) Liver
B) Bone marrow
C) Kidney
D) Brain
E) Adrenals



Answer:  C

A meta-analysis published by Afshari A. and Coll. showed that inhaled NO increases the risk of renal injury. It should continue to be used only as a short-term rescue therapy in right heart failure, pulmonary hypertension or in refractory hypoxemia. Also, methemoglobin levels should be monitored closely in those patients.



Reference:

Afshari A, Brok J, Møller AM, Wetterslev J. Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) and acute lung injury in children and adults. Cochrane Database Syst Rev 2010; :CD002787