Q: Which of the following vessel is usually involved in Locked-in syndrome? 

A) Basilar artery 
 B) Middle Cerebral artery 
C) Anterior Cerebral artery 
D) Internal Jugular artery 
E) Aortic multiple emboli (showering) 


Answer: A

Ventral pons infarction is the most common cause of locked-in syndrome due to basilar artery involvement. Other major cause of Locked-in syndrome is pontine hemorrhage, due to hypertension or vascular malformations. Other reported causes include trauma, infection (abscess), tumors, central pontine myelinolysis, and drug abuse.