Q: What is the major cause of meningitis in systemic lupus erythematosus(SLE) patients?


Answer:  Iatrogenic

Patients with SLE develops meningitis mostly due to medications, used for relief or treatment. It may be due to either direct cause from ibuprofen or azathioprine (aseptic meningitis) or may be due to medications causing immunosuppression, causing bacterial, cryptococcal or tuberculous meningitis.