Q: Osler's nodes can be a clinical finding in (select one)

A) Infective endocarditis
B) Systemic lupus erythematosus 
C) Disseminated gonococcal infection 
D) Distal to infected arterial catheter
E) All of the above



Answer:  E

Osler's nodes in contrast to Janeway's lesion are painful and raised lesions. They are mostly found in hands and feet. They are actually immune complex depositions. Though widely believed to be exclusive of infective endocarditis, they can be found in other conditions like in nonbacterial thrombotic endocarditis (marantic endocarditis), SLE, disseminated gonococcal infection and most importantly to be of note for intensivists, distal to infected arterial catheter.