Q: How cardiac drug Ivabradine works?


Answer: Ivabradine (Corlanor), approved by FDA in 2015 works in heart by acting at "Funny Channel" (yes! it is the name). It is indicated for angina and CHF, when patient either fail or cannot tolerate beta-blockers.  It is popularly known as "cardiotonic", as it is reported to decrease rate of hospitalizations related to CHF. Its major side effect is "luminous phenomena" (sensations of enhanced brightness around visual field). Also, it need to be use with caution due to its various drug interactions. 


Reference: 

Swedberg K, Komajda M, Böhm M, Borer JS, Ford I, Dubost-Brama A, Lerebours G, Tavazzi L; on behalf of the SHIFT Investigators (2010). "Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study". The Lancet. 376 (9744): 875–885.