Friday, April 21, 2017

Q: Can steroids be used as an added medicine during 'code' (ACLS) ?  (select one)

A) Yes
B) No

Answer:   A

Actually, some of the studies have been showing role of steroids particularly for In-Hospital-Cardiac-Arrest (IHCA) patients. Though vasopressin is no more a part of ACLS, it has been suggested to give as a "Epi-Vasopressin-Steroid" combo!



References:

1. Mentzelopoulos S, Zakynthinos S, Tzoufi M, et al. Vasopressin, epinephrine, and corticosteroids for in-hospital cardiac arrest. Arch Intern Med. 2009;169:15-24. PMID: 19139319. 

2. Mentzelopoulos S, Malachias S, Chamos C, et al. Vasopressin, steroids, and epinephrine and neurologically favorable survival after in-hospital cardiac arrest: a randomized clinical trial. JAMA. 2013;310(3):270-9. 

3. Varvarousi G, Stefaniotou A, Varavaroussis D, et al. Glucocorticoids as an emergency pharmacologic agent for cardiopulmonary resuscitation. Cardiovasc Drugs Ther. 2014;28:477-88. PMCID: PMC4163188..

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