Q: Chloramphenicol has an excellent blood brain barrier penetration?

A) True
B) False


Answer: True

Chloramphenicol due to its various side effects is not a drug of choice in most instances and particularly in developed countries. But it remained a valuable drug and in the list of WHO's list of essential medicines due to its excellent blood-brain barrier penetration, far superior to cephalosporins. It has excellent activity against Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae. Many authorities still recommend it as a drug of choice in the treatment of brain abscesses.