Padua Prediction Score

Q: Padua Prediction Score is designed to assess the risk of?

A) Venous ThromboEmbolism in hospitalized patients with liver disease
B) Pulmonary Embolism in hospitalized patients with liver disease
C) Venous ThromboEmbolism in hospitalized patients with renal disease
D) Pulmonary Embolism in hospitalized patients with renal disease


Answer: A

Padua Prediction score assesses the risk of Venous thromboembolism (VTE) in hospitalized patients with liver disease. Prophylaxis against VTE is highly under-utilized in patients with liver disease due to the misconception that they are "auto-anticoagulated" because their INR is high. INR is not a true indicator of auto-anticoagulation in patients with liver disease. Unfortunately, due to this misconception among medical staff, the adjusted hazard ratio (HR) of VTE in patients with the significant liver disease is 1.71, at lease shown in one study. 

One online calculator can be found here 


References: 

1. Ng KJ, Lee YK, Huang MY, et al. Risks of venous thromboembolism in patients with liver cirrhosis: a nationwide cohort study in Taiwan. J Thromb Haemost 2015; 13:206. Bogari H, Patanwala AE, Cosgrove R, Katz M. 

2. Risk-assessment and pharmacological prophylaxis of venous thromboembolism in hospitalized patients with chronic liver disease. Thromb Res 2014; 134:1220.