Q: All of the following are relatively contra-indicated in Serotonin Syndrome (SS) except?
Out of all of the above, Cyproheptadine is established as an antidote for SS. Cyproheptadine is a histamine-1 receptor antagonist as well as has anticholinergic activity. Benzodiazepines can also be used to control agitation.
Olanzapine is also recommended to counter SS but data is not convincing.
Chlorpromazine may increase hyperthermia.
Interestingly in SS, monitoring of tachycardia is used to gauge the effectiveness of treatment. Propranolol can mask tachycardia. Also, it can induce prolong hypotension due to it's prolong half life.
Bromocriptine is a serotonin agonist! - and should be avoided.
Dantrolene has no role in SS.
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