Sunday, June 3, 2018

Ischemic cholangiopathy after liver transplant

Q: What could be the risk to the transplanted liver with the use of a non-heart beating donor graft?

Answer: Ischemic cholangiopathy

Blood supply to the major bile ducts comes exclusively from the hepatic artery via the peribiliary plexus. Ischemic cholangiopathy mostly happened after liver transplantation, particularly with the use of a non-heart beating donor graft.



1. de Vries Y, von Meijenfeldt FA, Porte RJ. Post-transplant cholangiopathy: Classification, pathogenesis, and preventive strategies. Biochim Biophys Acta 2018; 1864:1507. 

2. Mourad MM, Algarni A, Liossis C, Bramhall SR. Aetiology and risk factors of ischaemic cholangiopathy after liver transplantation. World J Gastroenterol 2014; 20:6159. 

3. Cameron AM, Busuttil RW. Ischemic cholangiopathy after liver transplantation. Hepatobiliary Pancreat Dis Int 2005; 4:495.

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