Q: What is the median time period for the development of Immune reconstitution inflammatory syndrome (IRIS) after the initiation of Anti Retroviral Therapy (ART) in AIDS-related opportunistic infections?
Answer:
The median time period for the development of Immune reconstitution inflammatory syndrome (IRIS) after the initiation of Anti Retroviral Therapy (ART) is about 33 days. It can occur anywhere between 2 to 8 weeks.
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Reference:
Grant PM, Komarow L, Andersen J, et al. Risk factor analyses for immune reconstitution inflammatory syndrome in a randomized study of early vs. deferred ART during an opportunistic infection. PLoS One 2010; 5:e11416.
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