PH and cardiac function

Q: Increasing PH by infusion of bicarbonate (select one)

A) decreases the cardiac function
B) increases the cardiac function


Answer: A

One of the reason bicarbonate never find its place in "ACLS protocol" as it decreases the ionized calcium, and consequently decreases the cardiac function.

#acidbase
#cardiology


References:

Orchard CH, Kentish JC. Effects of changes of pH on the contractile function of cardiac muscle. Am J Physiol 1990; 258:C967.