Q: How quickly one apheresis unit of platelets (six units of pooled platelets) can be transfused?
Answer: About 20 to 30 minutes
Although platelets transfusion can be achieved within half hour of its availability, two factors should be taken into consideration. First, the predisposition of a patient to develop TACO (transfusion-associated circulatory overload ) and a patient's body size. Said that it is recommended that all platelet transfusions should be completed within four hours after they leave the blood bank.
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References:
1. Slichter SJ. Platelet transfusion therapy. Hematol Oncol Clin North Am 2007; 21:697.
2. McCullough J. Overview of platelet transfusion. Semin Hematol 2010; 47:235.
3. Alam A, Lin Y, Lima A, et al. The prevention of transfusion-associated circulatory overload. Transfus Med Rev 2013; 27:105.
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