Q: What is the pitfall of administrating excess oxygen to patients with acute decompensation of congestive heart failure (CHF)?
Answer: Although oxygen should be administrated to counter hypoxemia in patients with acute exacerbation of CHF, the excess of it may cause vasoconstriction and may cause counter-productive decrease in cardiac output. This again reinforce to treat oxygen as a drug.
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#pharmacology
Reference:
Park JH, Balmain S, Berry C, et al. Potentially detrimental cardiovascular effects of oxygen in patients with chronic left ventricular systolic dysfunction. Heart 2010; 96:533.
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