Friday, May 3, 2019

Activated Charcoal and ETOH poisoning

Q: Administration of activated charcoal (AC) should be administrated if a patient presents early with any type of alcohol poisoning? (select one) 

A) True
B) False


Answer: B

Common alcohols poisonings in ICU i.e.,

  • Acetone
  • Ethanol 
  • Ethylene glycol 
  • Isopropanol Methanol
do not get adsorb to AC - and are not recommended in acute alcohol poisonings.

Other stuff where AC is not helpful is metals like Arsenic, Lead, Mercury, Iron, Zinc and Cadmium. Also, inorganic ions like Lithium, Sodium, Calcium, Potassium, Magnesium, Fluoride and Iodide do not get adsorb to AC.

#toxicology



References:


1. Minocha A, Herold DA, Barth JT, et al. Activated charcoal in oral ethanol absorption: lack of effect in humans. J Toxicol Clin Toxicol 1986; 24:225.


2. Chyka PA, Seger D, Krenzelok EP, et al. Position paper: Single-dose activated charcoal. Clin Toxicol (Phila) 2005; 43:61. 


3. Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin Toxicol 1999; 37:731.

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