Q: What is Solvent/detergent-treated plasma (SD-plasma)?
Answer: Solvent/detergent-treated plasma (SD-plasma) is a processed plasma with solvents. Its main utility is to reduce the risk of transmission of enveloped viruses i.e. human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV).
When FFP is processed with solvent it not only dilutes and neutralizes the antibodies present in the plasma pool but also lowers the antibody against blood cells and plasma proteins.
#hematology
Reference:
Hellstern P. Fresh-frozen plasma, pathogen-reduced single-donor plasma or bio-pharmaceutical plasma? Transfus Apher Sci. 2008;39:69–74.
Answer: Solvent/detergent-treated plasma (SD-plasma) is a processed plasma with solvents. Its main utility is to reduce the risk of transmission of enveloped viruses i.e. human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV).
When FFP is processed with solvent it not only dilutes and neutralizes the antibodies present in the plasma pool but also lowers the antibody against blood cells and plasma proteins.
#hematology
Reference:
Hellstern P. Fresh-frozen plasma, pathogen-reduced single-donor plasma or bio-pharmaceutical plasma? Transfus Apher Sci. 2008;39:69–74.
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