Nimbex & hypothermia

Q: Hypothermia? (select one)

A) prolongs the effect of cisatracurium
B) shortens the effect of cisatracurium


Answer:  A

Hypothermia slows down the Hoffmann elimination process, resulting in prolonging the effect of cisatracurium.

#pharmacology
#neurology


Reference:

Kisor DF, Schmith VD. Clinical pharmacokinetics of cisatracurium besilate. Clin Pharmacokinet 1999; 36:27.