Q: A wedged sample of fat from pulmonary artery catheter (PAC) is more specific for diagnosis of Fat Embolism Syndrome (FES) than samples from bronchoalveolar lavage (BAL)?
A) True
B) False
Answer: B
Clinician should not place pulmonary artery catheter exclusively for the purpose of diagnosis of FES. Presence of fat from a wedged sample of pulmonary arterial blood is neither sensitive nor specific to diagnose FES. Also, there is no diagnostic criteria for fat analysis is available.
As a matter of fact, BAL samples with >30% of alveolar cells staining for neutral fat is found to be strongly associated with a clinical diagnosis of FES.
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Reference:
Mimoz O, Edouard A, Beydon L, Quillard J, Verra F, Fleury J, Bonnet F, Samii K. Contribution of bronchoalveolar lavage to the diagnosis of posttraumatic pulmonary fat embolism.Intensive Care Med. 1995; 21:973–980
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