Q: What is the correlation between high erythrocyte sedimentation rate (ESR) and End Stage Renal Disease (ESRD)?
Answer: None!
Elevated ESR is a norm in ESRD patients as well as in nephrotic syndrome patients, and it does not get effected by hemodialysis either. It has no clinical relevance in this patient population and should not lead clinicians to further expensive testings. This elevation in ESR is usually independent without any underlying disease, infection or malignancy.
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References:
1. Bathon J, Graves J, Jens P, et al. The erythrocyte sedimentation rate in end-stage renal failure. Am J Kidney Dis 1987; 10:34.
2. Shusterman N, Kimmel PL, Kiechle FL, et al. Factors influencing erythrocyte sedimentation in patients with chronic renal failure. Arch Intern Med 1985; 145:1796.
3. Arik N, Bedir A, Günaydin M, et al. Do erythrocyte sedimentation rate and C-reactive protein levels have diagnostic usefulness in patients with renal failure? Nephron 2000; 86:224.
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