killip classification

 Q: What is Killip classification? 

 Answer: The Killip classification is one of the cornerstones of prognostic predictors in acute Myocardial Infarction (MI). The following five parameters determine 90% of the prognostic predictors of 30-day mortality in acute MI: 

1.  age 
2.  systolic blood pressure (SBP) on presentation 
3.  Killip classification 
4.  heart rate, and 
5.  anatomic location of the MI 

 Killip classification itself is divided into four classes 

•  class I - no clinical signs of heart failure 
• class II - pulmonary crackles, an S 3 gallop, and elevated jugular venous pressure (JVP) 
• class III - frank acute pulmonary edema 
• class IV - signs of cardiogenic shock including hypotension, oliguria, cyanosis, or impaired mental status

#cardiology

References:

1. Lee KL, Woodlief LH, Topol EJ, et al, for the GUSTO-I investigators. Predictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. GUSTO-I Investigators. Circulation. 1995 Mar 15. 91 (6):1659-68 

2.  Khot UN, Jia G, Moliterno DJ, et al. Prognostic Importance of Physical Examination for Heart Failure in Non–ST-Elevation Acute Coronary Syndromes: The Enduring Value of Killip Classification. JAMA. 2003;290(16):2174–2181. doi:10.1001/jama.290.16.2174 

3.  Mello BH, Oliveira GB, Ramos RF, et al. Validation of the Killip-Kimball classification and late mortality after acute myocardial infarction. Arq Bras Cardiol. 2014;103(2):107-117. doi:10.5935/abc.20140091