CD associated cardic disease

Q: One of the clinical symptoms of cardiomyopathy associated with Chagas Disease (CD) is? (select one)

A) bradycardia out of proportion to fever

B) tachycardia out of proportion to fever 

Answer: B

Initial signs and symptoms of CD are usually benign. Interestingly, symptomatic myocarditis is typically mild if it occurs via the vector-borne route but severe if it occurs via the oral route. The clinical signs of cardiac involvement in an acute CD are dyspnea, fatigue, chest pain, arrhythmias, and sudden cardiac arrest.

Tachycardia out of proportion to fever is a non-specific sign but favors the diagnosis of CD.

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References:

1. Nunes MCP, Beaton A, Acquatella H, et al. Chagas Cardiomyopathy: An Update of Current Clinical Knowledge and Management: A Scientific Statement From the American Heart Association. Circulation 2018; 138:e169.

2. Parada H, Carrasco HA, Añez N, et al. Cardiac involvement is a constant finding in acute Chagas' disease: a clinical, parasitological and histopathological study. Int J Cardiol 1997; 60:49.

3.Bastos CJ, Aras R, Mota G, et al. Clinical outcomes of thirteen patients with acute chagas disease acquired through oral transmission from two urban outbreaks in northeastern Brazil. PLoS Negl Trop Dis 2010; 4:e711.